UBD/Jab_MPN module annotation
Jab_MPN domain binds directly to ubiquitin with an affinity comparable to other known UBDs, Proteins with this domain include proteasome regulatory subunits, eukaryotic initiation factor 3 (eIF3) subunits and regulators of transcription factors. They are metalloenzymes that function as the ubiquitin isopeptidase/ deubiquitinase in the ubiquitin-based signaling and protein turnover pathways in eukaryotes (1).
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Detail gene list for module UBD/Jab_MPN
