CFinderADM001265 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| tetrahydrofolate_biosynthetic_process | 0.001900073 | GO:0046654 |
| inositol trisphosphate metabolic process | 0.003481212 | GO:0032957 |
| glutamine metabolic process | 0.003481212 | GO:0006541 |
| GTP_cyclohydrolase_I_activity | 0.006270242 | GO:0003934 |
| inositol-1,3,4-trisphosphate_6-kinase_activity | 0.007050469 | GO:0052725 |
| inositol-1,3,4-trisphosphate_5-kinase_activity | 0.007050469 | GO:0052726 |
| inositol tetrakisphosphate 1-kinase activity | 0.007050469 | GO:0047325 |
| tetrahydrofolate biosynthesis II | 0.011228382 | plantCyc |
| arginine biosynthesis II (acetyl cycle) | 0.011228382 | plantCyc |
| UMP biosynthesis | 0.011228382 | plantCyc |
| 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) | 0.011228382 | plantCyc |
| 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza) | 0.011228382 | plantCyc |
| ornithine-citrulline shuttle | 0.011228382 | plantCyc |
| 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I | 0.011228382 | plantCyc |
| lipid-dependent phytate biosynthesis II (via Ins(1,3,4)P3) | 0.011228382 | plantCyc |
| arginine biosynthesis I (via L-ornithine) | 0.011228382 | plantCyc |
| glutamine degradation I | 0.011618866 | plantCyc |
| Folate_biosynthesis | 0.008546023 | KEGG |
| Alanine,_aspartate_and_glutamate_metabolism | 0.01043537 | KEGG |
| Phosphatidylinositol_signaling_system | 0.027695797 | KEGG |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g098630.2 | Mitochondrial inner membrane translocase complex, subunit Tim44-related protein | AT5G27395 (1.00E-95) |
| Solyc02g086780.2 | ||
| Solyc03g115630.2 | carbamoyl phosphate synthetase A | AT3G27740 (0) |
| Solyc04g056370.2 | AT1G04590 (7.00E-75) | |
| Solyc06g083230.2 | GTP cyclohydrolase I | AT3G07270 (1.00E-154) |
| Solyc08g015630.2 | inositol 1,3,4-trisphosphate 5/6-kinase 4 | AT2G43980 (4.00E-140) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| CFinderADM000267 | proteolysis transmembrane transport lipid metabolic process aspartic-type endopeptidase activity integral to membrane mitochondrial outer membrane methylglyoxal degradation I hydrolysis and/or rearrangement of glycosidic bonds Glycoside Hydrolases GH89 | details |
| CFinderADM000452 | tetrahydrofolate_biosynthetic_process GTP_cyclohydrolase_I_activity magnesium_ion_transport Transcription regulator: LUG magnesium_ion_transmembrane_transporter_activity acetylglucosaminyltransferase activity 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II volatile benzenoid biosynthesis I (ester formation) Folate_biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| CFinderADM000516 | tetrahydrofolate_biosynthetic_process GTP_cyclohydrolase_I_activity signal peptide processing signal peptidase complex Rho guanyl-nucleotide exchange factor activity hydrogen ion transporting ATP synthase activity, rotational mechanism peptidase activity proton-transporting ATPase activity, rotational mechanism proton-transporting ATP synthase complex, catalytic core F(1) ATP synthesis coupled proton transport endoplasmic reticulum integral to membrane intracellular protein transport 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II Folate_biosynthesis | details |
| CFinderADM000581 | retromer complex GTP_cyclohydrolase_I_activity isocitrate lyase activity tetrahydrofolate_biosynthetic_process proton-transporting ATP synthase complex, catalytic core F(1) retrograde transport, endosome to Golgi protein transporter activity cation binding catalytic activity proton-transporting ATPase activity, rotational mechanism hydrogen ion transporting ATP synthase activity, rotational mechanism 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II valine degradation I very long chain fatty acid biosynthesis I Folate_biosynthesis hydrolysis and/or rearrangement of glycosidic bonds Glycoside Hydrolases GH89 adenosine ribonucleotides de novo biosynthesis | details |
| CFinderADM000669 | tetrahydrofolate_biosynthetic_process cofactor binding GTP_cyclohydrolase_I_activity cytoplasm 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II TCA cycle II (plants and fungi) TCA cycle variation V (plant) triacylglycerol degradation Carbon_fixation_pathways_in_prokaryotes Retrograde_endocannabinoid_signaling Folate_biosynthesis | details |
| CFinderADM000793 | GTP_cyclohydrolase_I_activity tetrahydrofolate_biosynthetic_process fatty acid biosynthetic process 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II plant sterol biosynthesis Folate_biosynthesis Steroid_biosynthesis Lysosome | details |
| CFinderADM000827 | tetrahydrofolate_biosynthetic_process GTP_cyclohydrolase_I_activity 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II very long chain fatty acid biosynthesis I very long chain fatty acid biosynthesis II Folate_biosynthesis Peroxisome | details |
| CFinderADM000862 | GTP_cyclohydrolase_I_activity tetrahydrofolate_biosynthetic_process vacuolar proton-transporting V-type ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances proton transport E2: UBC 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II Folate_biosynthesis adenosine ribonucleotides de novo biosynthesis | details |
| CFinderADM001114 | PPC:4.5.3: Casein Kinase II Family tetrahydrofolate_biosynthetic_process GTP_cyclohydrolase_I_activity glutamine metabolic process cytoplasm 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I UMP biosynthesis arginine biosynthesis I (via L-ornithine) arginine biosynthesis II (acetyl cycle) glutamine degradation I ornithine-citrulline shuttle tetrahydrofolate biosynthesis II Retrograde_endocannabinoid_signaling Folate_biosynthesis Alanine,_aspartate_and_glutamate_metabolism Pantothenate_and_CoA_biosynthesis | details |
| CFinderADM001162 | tetrahydrofolate_biosynthetic_process GTP binding GTP_cyclohydrolase_I_activity 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II triacylglycerol degradation Retrograde_endocannabinoid_signaling Folate_biosynthesis | details |
| CFinderADM001186 | nucleus GTP_cyclohydrolase_I_activity tetrahydrofolate_biosynthetic_process mRNA processing regulation of transcription, DNA-dependent methyltransferase activity cytoplasm 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II Folate_biosynthesis | details |
| CFinderADM001235 | inositol trisphosphate metabolic process inositol tetrakisphosphate 1-kinase activity inositol-1,3,4-trisphosphate_5-kinase_activity inositol-1,3,4-trisphosphate_6-kinase_activity N-acetyltransferase_activity lipid-dependent phytate biosynthesis II (via Ins(1,3,4)P3) 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza) 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) Steroid_hormone_biosynthesis Phosphatidylinositol_signaling_system | details |
| CFinderADM001243 | tetrahydrofolate_biosynthetic_process PPC:4.5.3: Casein Kinase II Family GTP_cyclohydrolase_I_activity protein glycosylation galactosyltransferase activity 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II syringetin biosynthesis flavonol biosynthesis Folate_biosynthesis Glycosaminoglycan_biosynthesis_-_heparan_sulfate_/_heparin Flavonoid_biosynthesis Flavonoid_biosynthesis formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
Expression profiles
 Show details about module gene expression profiling |