TreatCFM001596 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| nucleus | 0.001993835 | GO:0005634 |
| nucleic acid binding | 0.009659388 | GO:0003676 |
| unfolded protein binding | 0.01461754 | GO:0051082 |
| protein folding | 0.015025485 | GO:0006457 |
| Ubiquitin_Proteasome_system, E3 adaptor: DDB1 | 3.48E-07 | gene family |
| Alzheimer's disease | 0.007320823 | KEGG |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g102990.2 | ATP-dependent Clp protease | AT5G49840 (7.00E-168) |
| Solyc02g021650.2 | damaged DNA binding protein 1A | AT4G05420 (0) |
| Solyc02g043860.2 | Insulinase (Peptidase family M16) family protein | AT1G06900 (0) |
| Solyc03g007100.2 | cleavage and polyadenylation specificity factor 160 | AT5G51660 (0) |
| Solyc04g049630.2 | alpha/beta-Hydrolases superfamily protein | AT5G36210 (0) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000235 | nucleocytoplasmic transport nuclear pore structural_constituent_of_nuclear_pore Protein_kinases_phosphatases, PPC:4.1.6: Unknown Function Kinase formation of glycosidic bonds, GlycosylTransferases: GTnc Ubiquitin_Proteasome_system, E3 adaptor: DDB1 | details |
| TreatCFM000541 | core TFIIH complex nucleotide-excision repair nuclease activity ATP-dependent DNA helicase activity unfolded protein binding Base excision repair Alzheimer's disease | details |
| TreatCFM000616 | Ubiquitin_Proteasome_system, E3 adaptor: DDB1 | details |
| TreatCFM001406 | protein folding Ubiquitin_Proteasome_system, E3 adaptor: DDB1 methylerythritol phosphate pathway I mevalonate pathway I trans, trans-farnesyl diphosphate biosynthesis methylerythritol phosphate pathway II Terpenoid backbone biosynthesis Alzheimer's disease | details |
Expression profiles
 Show details about module gene expression profiling |