TreatCFM000687 module
|
Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| methylenetetrahydrofolate reductase (NADPH) activity | 0.004318038 | GO:0004489 |
| methionine metabolic process | 0.004318038 | GO:0006555 |
| 3'-5' exonuclease activity | 0.017963356 | GO:0008408 |
| nucleobase-containing compound metabolic process | 0.027994614 | GO:0006139 |
| folate transformations II | 0.004139055 | plantCyc |
| Antifolate resistance | 0.01190064 | KEGG |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc05g007590.2 | Pyridoxal phosphate (PLP)-dependent transferases superfamily protein | AT5G26600 (1.00E-43) |
| Solyc05g055730.2 | methylenetetrahydrofolate reductase 2 | AT2G44160 (0) |
| Solyc06g065020.2 | Major facilitator superfamily protein | AT1G22540 (9.00E-177) |
| Solyc07g040730.1 | Protein of unknown function (DUF3511) | |
| Solyc11g013020.1 | ||
| Solyc12g094540.1 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000721 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity chromatin binding Transcription_related, Transcription regulator: MBF1 Transcription_related, Transcription regulator: PHD folate transformations II Pyruvate metabolism Antifolate resistance | details |
| TreatCFM000726 | nucleobase-containing compound metabolic process 3'-5' exonuclease activity Viral carcinogenesis | details |
| TreatCFM000763 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity nuclear chromosome chromatin remodeling oxidation-reduction process Cytochrome_P450, Cytochrome P450: CYP76B folate transformations II Monoterpenoid biosynthesis Antifolate resistance | details |
| TreatCFM001124 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity peptidase activity N-acetyltransferase_activity Transcription_related, Transcription factor: TUB Transcription_related, Transcription regulator: GNAT folate transformations II Antigen processing and presentation Antifolate resistance | details |
| TreatCFM001395 | methylenetetrahydrofolate reductase (NADPH) activity methionine metabolic process 3'-5' exonuclease activity nucleobase-containing compound metabolic process Ubiquitin_Proteasome_system, E2: UBC folate transformations II Antifolate resistance | details |
| TreatCFM001474 | methionine metabolic process tetrahydrofolate_biosynthetic_process methylenetetrahydrofolate reductase (NADPH) activity GTP_cyclohydrolase_I_activity cytoplasm Transcription_related, Transcription factor: TCP 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I tetrahydrofolate biosynthesis II folate transformations II Folate biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis Antifolate resistance | details |
| TreatCFM001511 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity oxidation-reduction process Cytochrome_P450, Cytochrome P450: CYP76B folate transformations II Monoterpenoid biosynthesis Antifolate resistance | details |
Expression profiles
 Show details about module gene expression profiling |