TissueCFM000846 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| ubiquitin ligase complex | 0.001726668 | GO:0000151 |
| retromer complex | 0.001726668 | GO:0030904 |
| ubiquitin-ubiquitin ligase activity | 0.016715833 | GO:0034450 |
| retrograde transport, endosome to Golgi | 0.018394902 | GO:0042147 |
| protein transport | 0.045857716 | GO:0015031 |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g106050.2 | dynamin-related protein 3A | AT4G33650 (0) |
| Solyc03g033400.2 | VPS35 homolog B | AT1G75850 (0) |
| Solyc04g011500.2 | actin-11 | AT3G12110 (0) |
| Solyc04g054140.2 | related to KPC1 | AT2G22010 (0) |
| Solyc04g076210.2 | ubiquitin-specific protease 16 | AT4G24560 (2.00E-141) |
| Solyc06g071800.2 | with no lysine (K) kinase 3 | AT3G48260 (5.00E-160) |
| Solyc09g007670.2 | Transducin/WD40 repeat-like superfamily protein | AT2G37160 (0) |
| Solyc10g086070.1 | Transducin/WD40 repeat-like superfamily protein | AT3G53390 (0) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000052 | DNA-directed DNA polymerase activity transcription, DNA-dependent DNA binding | details |
| TissueCFM000267 | ribonuclease activity mRNA processing protein ubiquitination protein phosphorylation lipid metabolic process Protein_kinases_phosphatases, PPC:5.2.1: Other Kinase Platinum drug resistance Drug metabolism - other enzymes | details |
| TissueCFM000288 | vacuole_organization pseudouridine synthase activity nucleobase-containing compound kinase activity RNA modification pseudouridine synthesis nucleobase-containing compound metabolic process intracellular protein transport adenosine ribonucleotides de novo biosynthesis Ribosome biogenesis in eukaryotes | details |
| TissueCFM000326 | Transcription_related, Transcription regulator: C3H | details |
| TissueCFM000335 | protein_farnesyltransferase_complex regulation_of_cell_proliferation protein_farnesylation protein_prenylation cellular metabolic process protein prenyltransferase activity Terpenoid backbone biosynthesis | details |
| TissueCFM000434 | ATP-dependent_5'-3'_DNA_helicase_activity DNA helicase activity Ubiquitin_Proteasome_system, E3 adaptor: DWD flavonol biosynthesis syringetin biosynthesis mRNA surveillance pathway Flavonoid biosynthesis Flavonoid biosynthesis | details |
| TissueCFM000449 | peptide_biosynthetic_process protein insertion into membrane ubiquitin protein ligase binding ubiquitin-dependent protein catabolic process Ubiquitin_Proteasome_system, E3 adaptor: Cullin Transcription_related, Transcription regulator: C3H | details |
| TissueCFM000509 | retromer complex microtubule Nicotinate and nicotinamide metabolism | details |
| TissueCFM000511 | ubiquitin ligase complex GPI-anchor transamidase complex F-actin capping protein complex ubiquitin-dependent protein catabolic process attachment_of_GPI_anchor_to_protein barbed-end_actin_filament_capping GPI-anchor_transamidase_activity ubiquitin-ubiquitin ligase activity exocyst Ubiquitin_Proteasome_system, E3 adaptor: Cullin Antigen processing and presentation | details |
| TissueCFM000601 | nuclear chromosome chromatin remodeling Homologous recombination | details |
| TissueCFM000732 | ubiquitin-dependent protein catabolic process proteasome_regulatory_particle,_base_subcomplex ubiquitin protein ligase binding Ubiquitin_Proteasome_system, E3 adaptor: Cullin | details |
| TissueCFM000802 | DNA recombination four-way junction helicase activity Synaptic vesicle cycle | details |
| TissueCFM000816 | actin_filament actin_nucleation histone acetylation transcription cofactor activity histone acetyltransferase activity Ubiquitin_Proteasome_system, DUB: USP Transcription_related, Transcription regulator: PHD Transcription_related, Transcription factor: C2H2 | details |
| TissueCFM000821 | protein arginylation actin cytoskeleton Arp2/3_protein_complex regulation of actin filament polymerization arginyltransferase activity Arp2/3_complex-mediated_actin_nucleation protein binding formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII dolichyl-diphosphooligosaccharide biosynthesis Various types of N-glycan biosynthesis | details |
| TissueCFM000831 | mediator complex regulation of transcription from RNA polymerase II promoter ATPase activity, coupled to transmembrane movement of substances RNA_polymerase_II_transcription_cofactor_activity Ubiquitin_Proteasome_system, DUB: USP Transcription_related, Transcription factor: MYB Epstein-Barr virus infection | details |
| TissueCFM000859 | attachment_of_GPI_anchor_to_protein vacuole_organization phosphoric ester hydrolase activity GPI-anchor transamidase complex intracellular protein transport 3-phosphoinositide biosynthesis | details |
| TissueCFM000948 | RNA processing Proteasome | details |
| TissueCFM000975 | details | |
| TissueCFM000979 | RNA processing nucleobase-containing compound metabolic process nucleobase-containing compound kinase activity adenosine ribonucleotides de novo biosynthesis Ribosome biogenesis in eukaryotes | details |
| TissueCFM000983 | regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity nucleic acid binding protein_kinase_binding | details |
| TissueCFM001011 | cellular metabolic process nucleotidyltransferase activity biosynthetic process | details |
| TissueCFM001094 | Golgi vesicle transport endoplasmic reticulum | details |
| TissueCFM001189 | proteasome_regulatory_particle,_base_subcomplex ubiquitin-dependent protein catabolic process Transcription_related, Transcription factor: HSF | details |
| TissueCFM001239 | vacuole_organization cytoplasm intracellular protein transport | details |
| TissueCFM001242 | F-actin capping protein complex barbed-end_actin_filament_capping transferase activity, transferring acyl groups 2-oxoglutarate decarboxylation to succinyl-CoA Lysine degradation | details |
| TissueCFM001268 | transcription_corepressor_activity GPI-anchor transamidase complex nucleus attachment_of_GPI_anchor_to_protein regulation of transcription, DNA-dependent transcription, DNA-dependent | details |
| TissueCFM001406 | glutaminyl-tRNA aminoacylation glutamine-tRNA ligase activity tRNA aminoacylation ligase activity, forming aminoacyl-tRNA and related compounds tRNA aminoacylation for protein translation cytoplasm N-acetyltransferase_activity aminoacyl-tRNA ligase activity nucleotide binding tRNA charging Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001445 | protein_deubiquitination thiol-dependent ubiquitinyl hydrolase activity GTPase activity Ubiquitin_Proteasome_system, DUB: USP Epstein-Barr virus infection | details |
| TissueCFM001453 | vesicle docking involved in exocytosis vesicle-mediated transport | details |
| TissueCFM001458 | core TFIIH complex nucleotide-excision repair regulation of transcription, DNA-dependent transcription, DNA-dependent Transcription_related, Transcription factor: BSD Transcription_related, Transcription factor: faR1 | details |
| TissueCFM001471 | U6_snRNA_binding U5_snRNA_binding TORC1_complex TOR_signaling nuclear pore spliceosomal complex nuclear mRNA splicing, via spliceosome | details |
Expression profiles
 Show details about module gene expression profiling |