TreatCFM001264 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| histone_H3_acetylation | 0.002216657 | GO:0043966 |
| regulation_of_DNA_methylation | 0.003877474 | GO:0044030 |
| histone acetyltransferase activity | 0.027583615 | GO:0004402 |
| Transcription_related, Transcription regulator: SNF2 | 0.042865594 | gene family |
| Transcription_related, Transcription factor: faR1 | 0.042865594 | gene family |
| Transcription_related, Transcription regulator: PHD | 0.042865594 | gene family |
| Transcription_related, Transcription factor: B3 | 0.042865594 | gene family |
| UTP and CTP dephosphorylation II | 0.042640959 | plantCyc |
| pyrimidine deoxyribonucleotides de novo biosynthesis I | 0.042640959 | plantCyc |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc02g050280.2 | SNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-related | AT1G50410 (0) |
| Solyc02g079020.2 | HSI2-like 1 | AT2G30470 (3.00E-132) |
| Solyc04g011500.2 | actin-11 | AT3G12110 (0) |
| Solyc07g062600.2 | Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger protein | AT3G14980 (6.00E-170) |
| Solyc08g016010.2 | apyrase 2 | AT5G18280 (2.00E-170) |
| Solyc08g078320.2 | ubiquitin-protein ligases | AT2G39810 (0) |
| Solyc09g075640.2 | FAR1-related sequence 11 | AT1G10240 (0) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000198 | isomerase activity ribonuclease III activity RNA processing glucose and glucose-1-phosphate degradation sucrose biosynthesis II UDP-glucose biosynthesis sucrose degradation III (sucrose invertase) starch biosynthesis Glycolysis / Gluconeogenesis Type II diabetes mellitus Proteoglycans in cancer | details |
| TreatCFM000201 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor metalloendopeptidase activity Transcription_related, Transcription factor: CPP L-glutamine biosynthesis II (tRNA-dependent) triacylglycerol biosynthesis Protein processing in endoplasmic reticulum Aminoacyl-tRNA biosynthesis Fat digestion and absorption Hippo signaling pathway -fly | details |
| TreatCFM000447 | G-protein coupled receptor signaling pathway FMN binding signal transducer activity guanyl nucleotide binding acyl-CoA dehydrogenase activity oxidoreductase activity, acting on the CH-CH group of donors G-protein_beta/gamma-subunit_complex_binding GTPase activity two-component signal transduction system (phosphorelay) oxidation-reduction process flavin adenine dinucleotide binding Transcription_related, Transcription regulator: Orphans Aminobenzoate degradation | details |
| TreatCFM000523 | details | |
| TreatCFM000525 | SAGA-type_complex aspartic-type endopeptidase activity transcription_corepressor_activity microtubule Protein_kinases_phosphatases, PPC:3.1.1: Casein Kinase I Family | details |
| TreatCFM000541 | core TFIIH complex nucleotide-excision repair nuclease activity ATP-dependent DNA helicase activity unfolded protein binding Base excision repair Alzheimer's disease | details |
| TreatCFM000546 | Parkinson's disease | details |
| TreatCFM000548 | Transcription_related, Transcription factor: trihelix Vibrio cholerae infection hydrolysis and/or rearrangement of glycosidic bonds， Glycoside Hydrolases： GH89 | details |
| TreatCFM000668 | N,N-dimethylaniline monooxygenase activity NADP binding flavin adenine dinucleotide binding | details |
| TreatCFM000717 | acyl-CoA metabolic process acyl-CoA_hydrolase_activity charged-tRNA amino acid modification tRNA A64-2'-O-ribosylphosphate transferase activity oligosaccharyltransferase complex protein N-linked glycosylation acyl-CoA hydrolysis ω-hydroxylation of caprate and laurate Protein processing in endoplasmic reticulum Bile secretion | details |
| TreatCFM000718 | charged-tRNA amino acid modification tRNA A64-2'-O-ribosylphosphate transferase activity SUMO_transferase_activity FMN binding | details |
| TreatCFM000732 | Vibrio cholerae infection Chemical carcinogenesis | details |
| TreatCFM000757 | microtubule GTPase activity microtubule-based process cell redox homeostasis Nicotinate and nicotinamide metabolism Vibrio cholerae infection | details |
| TreatCFM000766 | nucleic acid binding isocitrate dehydrogenase (NADP+) activity mRNA guanylyltransferase activity nucleotide binding alanine-tRNA ligase activity isocitrate metabolic process 7-methylguanosine mRNA capping alanyl-tRNA aminoacylation ligase activity, forming aminoacyl-tRNA and related compounds tRNA charging glutamine biosynthesis III mRNA surveillance pathway Aminoacyl-tRNA biosynthesis Lipopolysaccharide biosynthesis | details |
| TreatCFM000809 | microtubule microtubule-based process GTPase activity methyltransferase activity mRNA surveillance pathway Nicotinate and nicotinamide metabolism | details |
| TreatCFM000848 | Protein_kinases_phosphatases, PPC:4.5.4: GSK3/Shaggy Like Protein Kinase Family RNA degradation | details |
| TreatCFM000924 | histone_H3_acetylation spindle pole microtubule organizing center regulation_of_DNA_methylation Ino80_complex exocyst microtubule cytoskeleton organization exocytosis histone acetyltransferase activity Transcription_related, Transcription factor: faR1 Ubiquitin_Proteasome_system, E3: RING Transcription_related, Transcription regulator: PHD Transcription_related, Transcription regulator: SNF2 | details |
| TreatCFM000992 | glycerone kinase activity glycerol metabolic process Arp2/3_protein_complex cytoskeleton actin_filament_organization Arp2/3_complex-mediated_actin_nucleation FMN binding formation of glycosidic bonds, GlycosylTransferases: GTnc cytokinin-O-glucosides biosynthesis Zeatin biosynthesis RIG-I-like receptor signaling pathway Aminobenzoate degradation | details |
| TreatCFM001006 | proteolysis involved in cellular protein catabolic process proteasome core complex threonine-type endopeptidase activity ubiquitin-dependent protein catabolic process Proteasome | details |
| TreatCFM001132 | eukaryotic translation initiation factor 3 complex spindle_assembly translational initiation small protein activating enzyme activity translation_initiation_factor_binding translation initiation factor activity Ubiquitin_Proteasome_system, E1: ThiF Herpes simplex infection | details |
| TreatCFM001135 | Platinum drug resistance | details |
| TreatCFM001176 | glycerol metabolic process tRNA aminoacylation glycerone kinase activity tRNA binding cytoplasm aminoacyl-tRNA ligase activity Transcription_related, Transcription regulator: SNF2 tRNA charging Aminoacyl-tRNA biosynthesis RIG-I-like receptor signaling pathway | details |
| TreatCFM001199 | vesicle_fusion_with_Golgi_apparatus Golgi vesicle transport exocytosis Golgi membrane protein transporter activity exocyst intracellular protein transport | details |
| TreatCFM001265 | zinc ion binding Transcription_related, Transcription factor: faR1 Transcription_related, Transcription factor: B3 UTP and CTP dephosphorylation II pyrimidine deoxyribonucleotides de novo biosynthesis I | details |
| TreatCFM001266 | transcription factor TFIIA complex transcription initiation from RNA polymerase II promoter hydrolase activity formation of glycosidic bonds, GlycosylTransferases: GTnc UTP and CTP dephosphorylation II pyrimidine deoxyribonucleotides de novo biosynthesis I pyrimidine ribonucleotides interconversion UTP and CTP dephosphorylation I MicroRNAs in cancer | details |
| TreatCFM001280 | endoplasmic reticulum membrane adhesion to carbohydrates, Carbohydrate-Binding Modules: CBM48 Transcription_related, Transcription factor: bZIP | details |
| TreatCFM001304 | SUMO_transferase_activity cell redox homeostasis protein ubiquitination Ubiquitin_Proteasome_system, E3: RING Vibrio cholerae infection | details |
| TreatCFM001360 | proton-transporting two-sector ATPase complex, catalytic domain cis-Golgi network ATP metabolic process proton transport ER to Golgi vesicle-mediated transport mRNA processing hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ribonuclease III activity ATP hydrolysis coupled proton transport RNA processing Oxidative phosphorylation RNA degradation Proteoglycans in cancer | details |
| TreatCFM001373 | mRNA guanylyltransferase activity ubiquitin-specific_protease_activity 7-methylguanosine mRNA capping protein tyrosine/serine/threonine phosphatase activity protein_deubiquitination mRNA processing protein dephosphorylation Ubiquitin_Proteasome_system, DUB: OTU Transcription_related, Transcription factor: C2H2 mRNA surveillance pathway | details |
| TreatCFM001396 | GTP binding endoplasmic reticulum membrane small GTPase mediated signal transduction | details |
| TreatCFM001402 | histone_H2A_acetylation negative_regulation_of_transcription,_DNA-templated histone_H4_acetylation NuA4_histone_acetyltransferase_complex chromatin remodeling DNA repair Transcription_related, Transcription factor: MYB-RELATED | details |
| TreatCFM001412 | microtubule protein_deubiquitination microtubule-based process ubiquitin-specific_protease_activity GTPase activity Ubiquitin_Proteasome_system, DUB: OTU Ubiquitin_Proteasome_system, E3 adaptor: DWD Proteasome Nicotinate and nicotinamide metabolism | details |
| TreatCFM001429 | protein phosphorylation protein kinase activity ATP binding Protein_kinases_phosphatases, PPC:4.1.1: MAP3K Platinum drug resistance | details |
| TreatCFM001455 | sulfide oxidation III (sulfur dioxygenase) Sulfur metabolism | details |
| TreatCFM001458 | mediator complex regulation of transcription from RNA polymerase II promoter RNA_polymerase_II_transcription_cofactor_activity N-acetyltransferase_activity Transcription_related, Transcription regulator: MED7 Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII Transcription_related, Transcription regulator: GNAT formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001571 | protein tyrosine/serine/threonine phosphatase activity protein dephosphorylation mediator complex regulation of transcription from RNA polymerase II promoter RNA_polymerase_II_transcription_cofactor_activity N-acetyltransferase_activity Transcription_related, Transcription regulator: MED7 Transcription_related, Transcription regulator: GNAT phosphatidylglycerol biosynthesis I (plastidic) cardiolipin biosynthesis II phosphatidylglycerol biosynthesis II (non-plastidic) Glycerophospholipid metabolism EGFR tyrosine kinase inhibitor resistance Endocrine resistance | details |
| TreatCFM001578 | hydrolase activity methylglyoxal degradation I pyridine nucleotide cycling (plants) L-ascorbate biosynthesis I (L-galactose pathway) Ascorbate and aldarate metabolism Pyruvate metabolism RNA degradation | details |
| TreatCFM001588 | formation of glycosidic bonds, GlycosylTransferases: GTnc | details |
| TreatCFM001648 | Golgi_transport_complex RNA degradation | details |
Expression profiles
 Show details about module gene expression profiling |