TissueCFM000391 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| proton-transporting V-type ATPase, V0 domain | 0.006213501 | GO:0033179 |
| alanyl-tRNA aminoacylation | 0.007886707 | GO:0006419 |
| microtubule | 0.011020658 | GO:0005874 |
| tRNA aminoacylation | 0.015759117 | GO:0043039 |
| alanine-tRNA ligase activity | 0.017588427 | GO:0004813 |
| microtubule-based process | 0.025346243 | GO:0007017 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 0.026366694 | GO:0016876 |
| ATP hydrolysis coupled proton transport | 0.027495238 | GO:0015991 |
| nucleic acid binding | 0.03046862 | GO:0003676 |
| ATP binding | 0.03046862 | GO:0005524 |
| helicase activity | 0.04475392 | GO:0004386 |
| hydrogen ion transmembrane transporter activity | 0.04475392 | GO:0015078 |
| GTPase activity | 0.044995632 | GO:0003924 |
| tRNA charging | 0.014419528 | plantCyc |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g095710.2 | RNA helicase family protein | AT1G33390 (0) |
| Solyc01g097990.2 | Acyl-CoA N-acyltransferases (NAT) superfamily protein | |
| Solyc02g065360.2 | Protein of unknown function, DUF647 | AT2G23470 (4.00E-147) |
| Solyc03g097290.2 | Alanyl-tRNA synthetase | AT1G50200 (0) |
| Solyc04g081490.2 | tubulin beta-1 chain | AT1G75780 (0) |
| Solyc05g008930.2 | Protein kinase superfamily protein | AT1G18390 (1.00E-150) |
| Solyc06g075160.2 | SIT4 phosphatase-associated family protein | AT1G07990 (0) |
| Solyc07g049710.2 | ATPase, V0 complex, subunit E | AT5G55290 (2.00E-30) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000259 | transcription factor TFIID complex kinetochore U4/U6_x_U5_tri-snRNP_complex Pantothenate and CoA biosynthesis | details |
| TissueCFM000296 | proton-transporting V-type ATPase, V0 domain RNA processing ATP hydrolysis coupled proton transport | details |
| TissueCFM000352 | proton-transporting V-type ATPase, V0 domain ATP hydrolysis coupled proton transport biosynthetic process threonine biosynthesis isoleucine biosynthesis I (from threonine) 4-hydroxyphenylpyruvate biosynthesis aspartate biosynthesis aspartate degradation I rosmarinic acid biosynthesis I aspartate degradation II 4-hydroxybenzoate biosynthesis I (eukaryotes) | details |
| TissueCFM000353 | microtubule NADP_biosynthetic_process double-stranded RNA binding NAD+ kinase activity protein domain specific binding microtubule-based process GTPase activity NAD/NADH phosphorylation and dephosphorylation Nicotinate and nicotinamide metabolism | details |
| TissueCFM000416 | microtubule-based process microtubule transaminase activity acetylglucosaminyltransferase activity GTPase activity pyridoxal phosphate binding formation of glycosidic bonds, GlycosylTransferases: GTnc proline biosynthesis III arginine degradation VI (arginase 2 pathway) arginine degradation I (arginase pathway) L-Nδ-acetylornithine biosynthesis Nicotinate and nicotinamide metabolism Arginine and proline metabolism Hippo signaling pathway -fly | details |
| TissueCFM000486 | cell cycle arrest proton-transporting V-type ATPase, V0 domain cyclin-dependent protein kinase inhibitor activity ATP hydrolysis coupled proton transport nucleic acid binding hydrogen ion transmembrane transporter activity Transcription_related, Transcription regulator: C3H | details |
| TissueCFM000487 | proton-transporting V-type ATPase, V0 domain ATP hydrolysis coupled proton transport | details |
| TissueCFM000509 | retromer complex microtubule Nicotinate and nicotinamide metabolism | details |
| TissueCFM000515 | microtubule-based process microtubule GTPase activity Ubiquitin_Proteasome_system, E3 adaptor: F-box Nicotinate and nicotinamide metabolism Hippo signaling pathway -fly | details |
| TissueCFM000660 | protein_sumoylation cellular response to extracellular stimulus SUMO_transferase_activity cell growth microtubule-based process microtubule GTPase activity Transcription_related, Transcription regulator: PHD Nicotinate and nicotinamide metabolism | details |
| TissueCFM000725 | proton-transporting V-type ATPase, V0 domain RNA processing ATP hydrolysis coupled proton transport ubiquitin-dependent protein catabolic process hydrogen ion transmembrane transporter activity Ubiquitin_Proteasome_system, E3 adaptor: SKP1 | details |
| TissueCFM000870 | positive regulation of transcription elongation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter microtubule-based process microtubule metalloendopeptidase activity GTPase activity Ubiquitin_Proteasome_system, E2: UBC triacylglycerol biosynthesis Nicotinate and nicotinamide metabolism Choline metabolism in cancer | details |
| TissueCFM000929 | regulation of signal transduction microtubule microtubule-based process GTPase activity Nicotinate and nicotinamide metabolism | details |
| TissueCFM001071 | proton-transporting V-type ATPase, V0 domain ATP hydrolysis coupled proton transport biosynthetic process Transcription_related, Transcription factor: bHLH threonine biosynthesis aspartate degradation I isoleucine biosynthesis I (from threonine) aspartate biosynthesis 4-hydroxyphenylpyruvate biosynthesis rosmarinic acid biosynthesis I aspartate degradation II 4-hydroxybenzoate biosynthesis I (eukaryotes) | details |
| TissueCFM001077 | microtubule microtubule-based process Transcription_related, Transcription factor: bZIP Nicotinate and nicotinamide metabolism | details |
| TissueCFM001127 | microtubule steroid biosynthetic process microtubule-based process 3-beta-hydroxy-delta5-steroid dehydrogenase activity GTPase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Transcription_related, Transcription factor: C2H2 superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis UDP-D-galacturonate biosynthesis I (from UDP-D-glucuronate) L-ascorbate biosynthesis V UDP-sugars interconversion Nicotinate and nicotinamide metabolism Amino sugar and nucleotide sugar metabolism | details |
| TissueCFM001139 | GTPase activity microtubule microtubule-based process triacylglycerol degradation Nicotinate and nicotinamide metabolism hydrolysis and/or rearrangement of glycosidic bonds， Glycoside Hydrolases： GH89 | details |
| TissueCFM001316 | intracellular protein transport protein domain specific binding microtubule-based process GTPase activity microtubule Peroxisome Nicotinate and nicotinamide metabolism | details |
| TissueCFM001342 | voltage-gated chloride channel activity chloride transport Ubiquitin_Proteasome_system, E3 adaptor: F-box | details |
Expression profiles
 Show details about module gene expression profiling |