TissueCFM000740 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| centromeric DNA binding | 0.001900073 | GO:0019237 |
| kinetochore_assembly | 0.002849905 | GO:0051382 |
| kinetochore | 0.004318038 | GO:0000776 |
| Smc5-Smc6_complex | 0.005755312 | GO:0030915 |
| nucleic acid binding | 0.007179685 | GO:0003676 |
| Ubiquitin_Proteasome_system, E3 adaptor: DWD | 0.036740494 | gene family |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g107160.2 | Transducin/WD40 repeat-like superfamily protein | AT3G19590 (1.00E-168) |
| Solyc03g120340.2 | centromere protein C | |
| Solyc04g045630.2 | SCP1-like small phosphatase 5 | AT5G11860 (3.00E-97) |
| Solyc09g059310.2 | Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain | AT3G25150 (4.00E-76) |
| Solyc10g009220.2 | RNA-binding (RRM/RBD/RNP motifs) family protein | AT4G00830 (4.00E-158) |
| Solyc10g078730.1 | Nse4, component of Smc5/6 DNA repair complex | AT1G51130 (5.00E-100) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000282 | meiotic chromosome segregation kinetochore_assembly centromeric DNA binding kinetochore chromosome, centromeric region protein binding | details |
| TissueCFM000293 | kinetochore_assembly meiotic chromosome segregation centromeric DNA binding kinetochore transcription factor complex chromosome, centromeric region Transcription_related, Transcription factor: E2F-DP Transcription_related, Transcription factor: MYB | details |
| TissueCFM000411 | kinetochore kinetochore_assembly centromeric DNA binding Ubiquitin_Proteasome_system, E3 adaptor: DWD EGFR tyrosine kinase inhibitor resistance | details |
| TissueCFM000989 | protein kinase activity peptidyl-prolyl cis-trans isomerase activity protein_peptidyl-prolyl_isomerization protein phosphorylation protein folding intracellular Protein_kinases_phosphatases, PPC:5.2.1: Other Kinase Ubiquitin_Proteasome_system, E3 adaptor: DWD Cell cycle - yeast Cationic antimicrobial peptide (CAMP) resistance | details |
| TissueCFM001103 | exosome_(RNase_complex) | details |
Expression profiles
 Show details about module gene expression profiling |