TreatCFM001140 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| microtubule | 0.008261571 | GO:0005874 |
| protein domain specific binding | 0.015091395 | GO:0019904 |
| acid phosphatase activity | 0.015091395 | GO:0003993 |
| microtubule-based process | 0.022468904 | GO:0007017 |
| GTPase activity | 0.038628201 | GO:0003924 |
| phosphate acquisition | 0.006974714 | plantCyc |
| Tuberculosis | 0.01185689 | KEGG |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g088000.2 | S-adenosyl-L-methionine-dependent methyltransferases superfamily protein | AT3G60910 (2.00E-105) |
| Solyc01g097790.2 | Plant protein of unknown function (DUF868) | AT5G28150 (9.00E-108) |
| Solyc02g093370.2 | Sucrase/ferredoxin-like family protein | AT3G27570 (1.00E-77) |
| Solyc03g116350.2 | HVA22 homologue A | AT1G74520 (3.00E-64) |
| Solyc06g007340.2 | Thioredoxin superfamily protein | AT1G07080 (3.00E-73) |
| Solyc08g006890.2 | Tubulin/FtsZ family protein | AT4G14960 (0) |
| Solyc08g066530.2 | HAD superfamily, subfamily IIIB acid phosphatase | AT4G29260 (9.00E-74) |
| Solyc10g085160.1 | S-adenosyl-L-methionine-dependent methyltransferases superfamily protein | AT5G01470 (1.00E-88) |
| Solyc12g057110.2 | general regulatory factor 2 | AT1G78300 (2.00E-128) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000081 | microtubule microtubule-based process GTPase activity | details |
| TreatCFM000114 | oxidoreductase activity, acting on the CH-CH group of donors ubiquitin-protein ligase activity coenzyme A biosynthesis I Pantothenate and CoA biosynthesis Steroid hormone biosynthesis | details |
| TreatCFM000261 | mitochondrion_organization microtubule microtubule-based process GTPase activity ubiquitin-protein ligase activity Ubiquitin_Proteasome_system, E2: UBC | details |
| TreatCFM000384 | nickel cation binding nitrogen compound metabolic process steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GTPase activity UDP-L-rhamnose biosynthesis | details |
| TreatCFM000430 | microtubule-based process microtubule eukaryotic translation initiation factor 3 complex acid phosphatase activity GTPase activity translation initiation factor activity cytoplasm Ubiquitin_Proteasome_system, DUB: JAMM phosphate acquisition Tuberculosis | details |
| TreatCFM000535 | isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway dimethylallyl diphosphate biosynthetic process 4-hydroxy-3-methylbut-2-en-1-yl_diphosphate_reductase_activity microtubule microtubule-based process dimethylallyltranstransferase activity GTPase activity multicellular organismal development guanosine nucleotides degradation II methylerythritol phosphate pathway II methylerythritol phosphate pathway I guanosine nucleotides degradation I cis-zeatin biosynthesis pyrimidine salvage pathway adenosine nucleotides degradation I Zeatin biosynthesis Nicotinate and nicotinamide metabolism | details |
| TreatCFM000596 | riboflavin kinase activity microtubule riboflavin biosynthetic process microtubule-based process GTPase activity flavin biosynthesis I (bacteria and plants) Riboflavin metabolism | details |
| TreatCFM000608 | microtubule-based process microtubule GTPase activity Ubiquitin_Proteasome_system, DUB: USP Transcription_related, Transcription factor: MYB-RELATED Epstein-Barr virus infection | details |
| TreatCFM000619 | Ubiquitin_Proteasome_system, E3 adaptor: F-box acyl-CoA hydrolysis ω-hydroxylation of caprate and laurate | details |
| TreatCFM000624 | GTP binding acid phosphatase activity intracellular protein transport phosphate acquisition Tuberculosis | details |
| TreatCFM000692 | mitochondrion_organization microtubule-based process microtubule prenyltransferase activity protein serine/threonine kinase activity GTPase activity vitamin E biosynthesis (tocotrienols) Ubiquinone and other terpenoid-quinone biosynthesis | details |
| TreatCFM000813 | microtubule microtubule-based process GTPase activity methyltransferase activity | details |
| TreatCFM000839 | microtubule microtubule-based process acid phosphatase activity GTPase activity phosphate acquisition GDP-mannose biosynthesis L-ascorbate biosynthesis I (L-galactose pathway) Nicotinate and nicotinamide metabolism Biofilm formation - Pseudomonas aeruginosa Tuberculosis | details |
| TreatCFM000864 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3-beta-hydroxy-delta5-steroid dehydrogenase activity steroid biosynthetic process oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis | details |
| TreatCFM000882 | transcription factor activity,transcription factor binding microtubule-based process GTPase activity microtubule Transcription_related, Transcription factor: GRAS pseudouridine degradation folate transformations II One carbon pool by folate Pyrimidine metabolism | details |
| TreatCFM000930 | mitochondrial_fission GTPase activator activity acid phosphatase activity phosphate acquisition Tuberculosis | details |
| TreatCFM001051 | microtubule 3-hydroxyacyl-CoA_dehydrogenase_activity fructose_1,6-bisphosphate_1-phosphatase_activity phosphoric ester hydrolase activity Ubiquitin_Proteasome_system, E3 adaptor: F-box Transcription_related, Transcription factor: bZIP Insulin signaling pathway Caprolactam degradation PPAR signaling pathway Alzheimer's disease | details |
| TreatCFM001126 | vacuolar proton-transporting V-type ATPase, V1 domain hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances protein domain specific binding proton-transporting ATPase activity, rotational mechanism ATP hydrolysis coupled proton transport Ubiquitin_Proteasome_system, E2: UBC indole-3-acetate activation I acyl-CoA hydrolysis ω-hydroxylation of caprate and laurate adenosine ribonucleotides de novo biosynthesis | details |
| TreatCFM001137 | heat shock protein binding unfolded protein binding acid phosphatase activity phosphate acquisition RNA degradation Tuberculosis | details |
| TreatCFM001139 | mRNA_3'-end_processing protein domain specific binding Transcription_related, Transcription factor: C2H2 | details |
| TreatCFM001141 | nucleoside metabolic process acyl-CoA hydrolysis ω-hydroxylation of caprate and laurate Terpenoid backbone biosynthesis Ubiquinone and other terpenoid-quinone biosynthesis | details |
| TreatCFM001142 | methyltransferase activity γ-glutamyl cycle Glutathione metabolism | details |
| TreatCFM001160 | microtubule-based process microtubule acid phosphatase activity GTPase activity phosphate acquisition Tuberculosis | details |
| TreatCFM001197 | intracellular protein transport acid phosphatase activity intracellular phosphate acquisition Chemical carcinogenesis Tuberculosis | details |
| TreatCFM001309 | microtubule-based process microtubule acid phosphatase activity heat shock protein binding unfolded protein binding GTPase activity Ubiquitin_Proteasome_system, DUB: USP phosphate acquisition Tuberculosis | details |
| TreatCFM001341 | microtubule microtubule-based process GTPase activity hydroxyacylglutathione hydrolase activity phosphoribosylanthranilate isomerase activity methylglyoxal_catabolic_process_to_D-lactate tryptophan metabolic process biosynthetic process coenzyme A biosynthesis I methylglyoxal degradation I tryptophan biosynthesis Pyruvate metabolism Phenylalanine, tyrosine and tryptophan biosynthesis Pantothenate and CoA biosynthesis Nicotinate and nicotinamide metabolism | details |
| TreatCFM001410 | microtubule microtubule-based process GTPase activity hydrolase activity aspartic-type endopeptidase activity pyrimidine salvage pathway guanosine nucleotides degradation II guanosine nucleotides degradation I adenosine nucleotides degradation I UTP and CTP dephosphorylation I Nicotinate and nicotinamide metabolism Purine metabolism | details |
| TreatCFM001425 | ATP hydrolysis coupled proton transport vacuolar proton-transporting V-type ATPase, V1 domain proton-transporting V-type ATPase, V0 domain protein domain specific binding hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances proton-transporting ATPase activity, rotational mechanism hydrogen ion transmembrane transporter activity Transcription_related, Transcription factor: C2H2 adenosine ribonucleotides de novo biosynthesis | details |
| TreatCFM001471 | mitochondrial_fission acid phosphatase activity vesicle-mediated transport protein binding phosphate acquisition Tuberculosis | details |
| TreatCFM001538 | vesicle docking Golgi vesicle transport mitochondrial_fission endoplasmic reticulum acid phosphatase activity four-way junction helicase activity DNA recombination exocytosis cytoplasm 4-aminobutyrate degradation 4-aminobutyrate degradation IV glutamate degradation IV phosphate acquisition Proteasome Nicotinate and nicotinamide metabolism Tuberculosis | details |
| TreatCFM001589 | acid phosphatase activity zinc ion binding transferase activity, transferring glycosyl groups formation of glycosidic bonds, GlycosylTransferases: GTnc Ubiquitin_Proteasome_system, DUB: USP phosphate acquisition L-ascorbate biosynthesis I (L-galactose pathway) GDP-mannose biosynthesis Biofilm formation - Pseudomonas aeruginosa Tuberculosis Chemical carcinogenesis | details |
| TreatCFM001610 | histone_H2A_acetylation negative_regulation_of_transcription,_DNA-templated histone_H4_acetylation NuA4_histone_acetyltransferase_complex chromatin remodeling protein domain specific binding DNA repair Transcription_related, Transcription factor: MYB-RELATED Transcription_related, Transcription factor: C2H2 | details |
| TreatCFM001659 | proteasome_regulatory_particle,_base_subcomplex acid phosphatase activity four-way junction helicase activity DNA recombination ubiquitin-dependent protein catabolic process phosphate acquisition Proteasome Tuberculosis | details |
Expression profiles
 Show details about module gene expression profiling |