TreatCFM000857 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| protein tyrosine phosphatase activity | 0.047789736 | GO:0004725 |
| Transcription_related, Transcription factor: NF-YA | 0.018052905 | gene family |
| Transcription_related, Transcription factor: Alfin-like | 0.018052905 | gene family |
| Ubiquitin_Proteasome_system, E3: RING | 0.023530698 | gene family |
| Cytochrome_P450, Cytochrome P450: CYP76B | 0.026187461 | gene family |
| UDP-L-rhamnose biosynthesis | 0.001438642 | plantCyc |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g008490.2 | nuclear factor Y, subunit A1 | AT5G12840 (7.00E-43) |
| Solyc01g102750.2 | alfin-like 6 | AT1G14510 (1.00E-92) |
| Solyc01g110390.2 | LYR family of Fe/S cluster biogenesis protein | AT4G34700 (4.00E-49) |
| Solyc03g059310.2 | Transducin/WD40 repeat-like superfamily protein | AT3G18140 (3.00E-117) |
| Solyc04g008020.2 | Zinc finger, C3HC4 type (RING finger) family protein | AT1G68070 (8.00E-111) |
| Solyc07g062130.2 | rhamnose biosynthesis 1 | AT1G78570 (0) |
| Solyc09g091790.2 | proteolysis 1 | AT3G24800 (6.00E-83) |
| Solyc09g098610.1 | cytochrome P450, family 76, subfamily C, polypeptide 1 | AT2G45570 (3.00E-111) |
| Solyc11g016990.1 | protein tyrosine phosphatase 1 | AT1G71860 (1.00E-119) |
| Solyc11g044270.1 | Major facilitator superfamily protein | AT5G64500 (3.00E-54) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TreatCFM000183 | exosome_(RNase_complex) Ubiquitin_Proteasome_system, E3 adaptor: DWD Cytochrome_P450, Cytochrome P450: CYP76B | details |
| TreatCFM000384 | nickel cation binding nitrogen compound metabolic process steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GTPase activity UDP-L-rhamnose biosynthesis | details |
| TreatCFM000428 | transport 3-beta-hydroxy-delta5-steroid dehydrogenase activity isomerase activity steroid biosynthetic process UDP-L-rhamnose biosynthesis trehalose degradation II (trehalase) syringetin biosynthesis flavonol biosynthesis Terpenoid backbone biosynthesis Flavonoid biosynthesis Galactose metabolism Flavonoid biosynthesis | details |
| TreatCFM000482 | Transcription_related, Transcription factor: Alfin-like formation of glycosidic bonds, GlycosylTransferases: GTnc cytokinin-O-glucosides biosynthesis Zeatin biosynthesis | details |
| TreatCFM000618 | protein_peptidyl-prolyl_isomerization Cytochrome_P450, Cytochrome P450: CYP76B Phenylpropanoid biosynthesis Monoterpenoid biosynthesis Cationic antimicrobial peptide (CAMP) resistance | details |
| TreatCFM000683 | peroxiredoxin activity steroid biosynthetic process FAD binding oxidation-reduction process 3-beta-hydroxy-delta5-steroid dehydrogenase activity coenzyme binding Ubiquitin_Proteasome_system, E3 adaptor: DWD UDP-L-rhamnose biosynthesis Phenylpropanoid biosynthesis Apoptosis - fly | details |
| TreatCFM000693 | autophagic vacuole assembly 3-beta-hydroxy-delta5-steroid dehydrogenase activity steroid biosynthetic process oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor cytoplasm UDP-L-rhamnose biosynthesis | details |
| TreatCFM000694 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid biosynthetic process UDP-L-rhamnose biosynthesis | details |
| TreatCFM000763 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity nuclear chromosome chromatin remodeling oxidation-reduction process Cytochrome_P450, Cytochrome P450: CYP76B folate transformations II Monoterpenoid biosynthesis Antifolate resistance | details |
| TreatCFM000864 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3-beta-hydroxy-delta5-steroid dehydrogenase activity steroid biosynthetic process oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis | details |
| TreatCFM001071 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid biosynthetic process UDP-L-rhamnose biosynthesis | details |
| TreatCFM001149 | mediator complex cyclin-dependent protein kinase regulator activity protein_kinase_binding regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid biosynthetic process UDP-L-rhamnose biosynthesis | details |
| TreatCFM001177 | phosphatidylinositol phosphorylation 3-beta-hydroxy-delta5-steroid dehydrogenase activity steroid biosynthetic process oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis D-myo-inositol (1,4,5)-trisphosphate degradation Glycine, serine and threonine metabolism Phosphatidylinositol signaling system | details |
| TreatCFM001223 | ER to Golgi vesicle-mediated transport cis-Golgi network | details |
| TreatCFM001245 | glycolipid transport glycolipid transporter activity prenyltransferase activity glycolipid binding steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis EGFR tyrosine kinase inhibitor resistance | details |
| TreatCFM001260 | aromatic amino acid family biosynthetic process 3-deoxy-7-phosphoheptulonate synthase activity Transcription_related, Transcription factor: C2H2 3-dehydroquinate biosynthesis I Terpenoid backbone biosynthesis Quorum sensing | details |
| TreatCFM001274 | protein binding Transcription_related, Transcription factor: NF-YA Protein processing in endoplasmic reticulum | details |
| TreatCFM001275 | mitochondrial matrix Transcription_related, Transcription factor: NF-YA | details |
| TreatCFM001294 | mitochondrial outer membrane coenzyme A biosynthetic process glutamine metabolic process dephospho-CoA kinase activity nucleosome Transcription_related, Transcription factor: Alfin-like arginine biosynthesis I (via L-ornithine) coenzyme A biosynthesis I UMP biosynthesis ornithine-citrulline shuttle arginine biosynthesis II (acetyl cycle) glutamine degradation I thioredoxin pathway Pantothenate and CoA biosynthesis Alanine, aspartate and glutamate metabolism Selenocompound metabolism | details |
| TreatCFM001295 | mediator complex cyclin-dependent protein kinase regulator activity protein_kinase_binding FAD binding regulation_of_cyclin-dependent_protein_serine/threonine_kinase_activity 3-beta-hydroxy-delta5-steroid dehydrogenase activity steroid biosynthetic process UDP-L-rhamnose biosynthesis pyridine nucleotide cycling (plants) | details |
| TreatCFM001302 | steroid biosynthetic process protein_peptidyl-prolyl_isomerization peptidyl-prolyl cis-trans isomerase activity 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis Cationic antimicrobial peptide (CAMP) resistance | details |
| TreatCFM001426 | steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor aspartic-type endopeptidase activity UDP-L-rhamnose biosynthesis syringetin biosynthesis flavonol biosynthesis Flavonoid biosynthesis Flavonoid biosynthesis | details |
| TreatCFM001476 | steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor aspartic-type endopeptidase activity Ubiquitin_Proteasome_system, E3 adaptor: DWD UDP-L-rhamnose biosynthesis syringetin biosynthesis flavonol biosynthesis Flavonoid biosynthesis Flavonoid biosynthesis | details |
| TreatCFM001502 | FAD binding Cytochrome_P450, Cytochrome P450: CYP76B Monoterpenoid biosynthesis | details |
| TreatCFM001511 | methionine metabolic process methylenetetrahydrofolate reductase (NADPH) activity oxidation-reduction process Cytochrome_P450, Cytochrome P450: CYP76B folate transformations II Monoterpenoid biosynthesis Antifolate resistance | details |
| TreatCFM001563 | cysteine biosynthetic process from serine phosphatase activator activity serine O-acetyltransferase activity cytoplasm Cytochrome_P450, Cytochrome P450: CYP76B seleno-amino acid biosynthesis cysteine biosynthesis I Monoterpenoid biosynthesis Biofilm formation - vibrio cholerae Cationic antimicrobial peptide (CAMP) resistance | details |
| TreatCFM001593 | mitochondrial outer membrane translocase complex protein import into mitochondrial outer membrane Cytochrome_P450, Cytochrome P450: CYP76B Base excision repair Monoterpenoid biosynthesis Herpes simplex infection | details |
| TreatCFM001598 | protein tyrosine phosphatase activity steroid biosynthetic process 3-beta-hydroxy-delta5-steroid dehydrogenase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor UDP-L-rhamnose biosynthesis EGFR tyrosine kinase inhibitor resistance | details |
Expression profiles
 Show details about module gene expression profiling |