TissueCFM001184 module
|
Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
| This network produced by cytoscapeweb |
Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| Arp2/3_protein_complex | 0.00996118 | GO:0005885 |
| actin cytoskeleton | 0.00996118 | GO:0015629 |
| Arp2/3_complex-mediated_actin_nucleation | 0.012643582 | GO:0034314 |
| regulation of actin filament polymerization | 0.012643582 | GO:0030833 |
| protein glycosylation | 0.02676419 | GO:0006486 |
| galactosyltransferase activity | 0.036880515 | GO:0008378 |
| Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII | 0.018817186 | gene family |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.023194632 | gene family |
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | 0.019896569 | KEGG |
| Platinum drug resistance | 0.047208047 | KEGG |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g067400.2 | Protein kinase superfamily protein | AT5G18610 (0) |
| Solyc04g008510.2 | UBX domain-containing protein | AT1G14570 (4.00E-147) |
| Solyc05g006470.2 | actin-related protein C1A | AT2G30910 (8.00E-167) |
| Solyc06g007440.2 | SOS3-interacting protein 4 | AT2G30360 (3.00E-126) |
| Solyc06g009650.2 | Vps51/Vps67 family (components of vesicular transport) protein | AT4G02030 (0) |
| Solyc08g081920.2 | Galactosyltransferase family protein | AT5G53340 (1.00E-130) |
| Solyc12g089140.1 | Erythronate-4-phosphate dehydrogenase family protein | AT1G75180 (1.00E-92) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000290 | iron_ion_transmembrane_transport iron ion transmembrane transporter activity integral to membrane GTP binding | details |
| TissueCFM000494 | lipid transport lipid transporter activity mRNA processing formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription regulator: C3H xylogalacturonan biosynthesis Hippo signaling pathway -fly | details |
| TissueCFM000561 | Arp2/3_protein_complex intracellular transport actin_filament_organization Arp2/3_complex-mediated_actin_nucleation formation of glycosidic bonds, GlycosylTransferases: GTnc dolichyl-diphosphooligosaccharide biosynthesis N-Glycan biosynthesis | details |
| TissueCFM000609 | protein insertion into membrane Ubiquitin_Proteasome_system, E3 adaptor: DWD triacylglycerol degradation Retrograde endocannabinoid signaling Herpes simplex infection | details |
| TissueCFM000622 | L-phenylalanine biosynthetic process protein N-linked glycosylation prephenate dehydratase activity beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc phenylalanine biosynthesis II phenylalanine biosynthesis (cytosolic, plants) | details |
| TissueCFM000786 | protein import into mitochondrial outer membrane protein neddylation NEDD8_activating_enzyme_activity acid-amino acid ligase activity mitochondrial outer membrane translocase complex small protein activating enzyme activity Ubiquitin_Proteasome_system, E1: ThiF | details |
| TissueCFM000796 | Base excision repair | details |
| TissueCFM000797 | threonine-type endopeptidase activity proteolysis involved in cellular protein catabolic process proteasome core complex endopeptidase activity proteasome core complex, alpha-subunit complex ubiquitin-dependent protein catabolic process Proteasome Base excision repair | details |
| TissueCFM000821 | protein arginylation actin cytoskeleton Arp2/3_protein_complex regulation of actin filament polymerization arginyltransferase activity Arp2/3_complex-mediated_actin_nucleation protein binding formation of glycosidic bonds, GlycosylTransferases: GTnc Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII dolichyl-diphosphooligosaccharide biosynthesis Various types of N-glycan biosynthesis | details |
| TissueCFM000873 | ubiquitin-specific_protease_activity peptidyl-prolyl cis-trans isomerase activity protein_peptidyl-prolyl_isomerization ubiquitin-dependent protein catabolic process signal transduction protein folding Ubiquitin_Proteasome_system, DUB: UCH | details |
| TissueCFM000877 | transcription_corepressor_activity Protein_kinases_phosphatases, PPC:1.16.1: Receptor Like Cytoplasmic Kinase II triacylglycerol degradation Retrograde endocannabinoid signaling Platinum drug resistance Endocrine resistance | details |
| TissueCFM000904 | prefoldin complex lipoate biosynthetic process ribosome lipoate synthase activity aminoacyl-tRNA_editing_activity translation 4 iron, 4 sulfur cluster binding structural constituent of ribosome lipoate biosynthesis and incorporation II lipoate biosynthesis and incorporation I tRNA charging Lipoic acid metabolism Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001174 | Cell cycle - yeast | details |
| TissueCFM001181 | proteolysis involved in cellular protein catabolic process proteasome core complex threonine-type endopeptidase activity proteasome core complex, alpha-subunit complex endopeptidase activity ubiquitin-dependent protein catabolic process Ubiquitin_Proteasome_system, DUB: JAMM Proteasome | details |
| TissueCFM001286 | Cdc73/Paf1 complex histone modification transcription elongation from RNA polymerase II promoter galactosyltransferase activity cellular amino acid metabolic process protein glycosylation methyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc thiosulfate disproportionation III (rhodanese) homoserine biosynthesis Sulfur relay system Monobactam biosynthesis Glycosaminoglycan biosynthesis - heparan sulfate / heparin | details |
| TissueCFM001359 | transcription elongation from RNA polymerase II promoter Golgi vesicle transport histone modification vesicle docking Cdc73/Paf1 complex protein glycosylation exocytosis galactosyltransferase activity endoplasmic reticulum Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII formation of glycosidic bonds, GlycosylTransferases: GTnc Glycosaminoglycan biosynthesis - heparan sulfate / heparin | details |
| TissueCFM001383 | protein_prenylation protein N-linked glycosylation via asparagine protein prenyltransferase activity endoplasmic reticulum membrane protein ubiquitination cell redox homeostasis Protein processing in endoplasmic reticulum Vibrio cholerae infection | details |
| TissueCFM001426 | ATP-dependent peptidase activity galactosyltransferase activity protein glycosylation helicase activity formation of glycosidic bonds, GlycosylTransferases: GTnc Glycosaminoglycan biosynthesis - heparan sulfate / heparin Herpes simplex infection | details |
| TissueCFM001431 | CAAX-box_protein_processing phosphatidylinositol phosphorylation metalloendopeptidase activity peptidase activity D-myo-inositol (1,4,5)-trisphosphate degradation Phosphatidylinositol signaling system Terpenoid backbone biosynthesis | details |
Expression profiles
 Show details about module gene expression profiling |