TissueCFM000622 module
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Protein:Yellow color--query protein Green color--interaction proteins.
Interaction line: Pink--proteins own interaction and positive co-expression relationship with target protein Blue--proteins own interaction and negative co-expression relationship with target protein Orange--proteins own interaction and protein-protein relationship with target protein |
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Module annotation (GSEA enrichment result)
| Function Annotation | FDR | Gene Ontology |
|---|---|---|
| L-phenylalanine biosynthetic process | 0.028090484 | GO:0009094 |
| protein N-linked glycosylation | 0.028090484 | GO:0006487 |
| prephenate dehydratase activity | 0.039999399 | GO:0004664 |
| beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | 0.039999399 | GO:0003830 |
| formation of glycosidic bonds, GlycosylTransferases: GTnc | 0.015022129 | gene family |
| phenylalanine biosynthesis II | 0.010630013 | plantCyc |
| phenylalanine biosynthesis (cytosolic, plants) | 0.010630013 | plantCyc |
Module member annotation
| Gene ID | Annotation | Ortholog in Arabidopsis (Blast e-value) |
|---|---|---|
| Solyc01g100820.2 | Clathrin adaptor complexes medium subunit family protein | AT1G56590 (0) |
| Solyc02g093430.2 | beta-1,4-N-acetylglucosaminyltransferase family protein | AT3G27540 (5.00E-180) |
| Solyc03g117030.1 | Polynucleotidyl transferase, ribonuclease H-like superfamily protein | AT2G32070 (7.00E-130) |
| Solyc04g076230.2 | Clathrin adaptor complexes medium subunit family protein | AT4G24550 (0) |
| Solyc05g050600.2 | dynamin-like protein | AT5G42080 (0) |
| Solyc06g007440.2 | SOS3-interacting protein 4 | AT2G30360 (3.00E-126) |
| Solyc06g076450.2 | RAB GTPase homolog A2B | AT1G07410 (2.00E-108) |
| Solyc06g083730.2 | Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain | AT5G43960 (8.00E-73) |
| Solyc07g065020.2 | protein phosphatase X 2 | AT5G55260 (4.00E-175) |
| Solyc08g008250.1 | calmodulin binding;purine nucleotide binding | AT1G13870 (8.00E-99) |
| Solyc08g076670.2 | SNARE associated Golgi protein family | AT4G17790 (1.00E-110) |
| Solyc08g081920.2 | Galactosyltransferase family protein | AT5G53340 (1.00E-130) |
| Solyc08g083070.2 | Tetratricopeptide repeat (TPR)-like superfamily protein | AT5G41950 (0) |
| Solyc10g008480.2 | Protein of unknown function (DUF789) | AT4G03420 (9.00E-119) |
| Solyc10g084210.1 | syntaxin of plants 71 | AT3G09740 (6.00E-97) |
| Solyc11g033280.1 | eukaryotic initiation factor 4A-III | AT3G19760 (0) |
| Solyc11g072520.1 | arogenate dehydratase 2 | AT3G07630 (9.00E-134) |
| Solyc12g088730.1 | Ribosomal protein L4/L1 family | AT2G20060 (4.00E-136) |
| Solyc12g089140.1 | Erythronate-4-phosphate dehydrogenase family protein | AT1G75180 (1.00E-92) |
Direct connection functional modules
| Module ID | Function Annotation | Overlap condition |
|---|---|---|
| TissueCFM000290 | iron_ion_transmembrane_transport iron ion transmembrane transporter activity integral to membrane GTP binding | details |
| TissueCFM000341 | protein N-linked glycosylation beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity proton-transporting two-sector ATPase complex, catalytic domain ATP hydrolysis coupled proton transport proton-transporting ATPase activity, rotational mechanism transferase activity, transferring acyl groups other than amino-acyl groups formation of glycosidic bonds, GlycosylTransferases: GTnc UDP-D-xylose biosynthesis N-Glycan biosynthesis | details |
| TissueCFM000450 | DNA replication single-stranded DNA binding Transcription_related, Transcription regulator: ARID valine degradation I beta-Alanine metabolism Herpes simplex infection | details |
| TissueCFM000494 | lipid transport lipid transporter activity mRNA processing formation of glycosidic bonds, GlycosylTransferases: GTnc Transcription_related, Transcription regulator: C3H xylogalacturonan biosynthesis Hippo signaling pathway -fly | details |
| TissueCFM000561 | Arp2/3_protein_complex intracellular transport actin_filament_organization Arp2/3_complex-mediated_actin_nucleation formation of glycosidic bonds, GlycosylTransferases: GTnc dolichyl-diphosphooligosaccharide biosynthesis N-Glycan biosynthesis | details |
| TissueCFM000609 | protein insertion into membrane Ubiquitin_Proteasome_system, E3 adaptor: DWD triacylglycerol degradation Retrograde endocannabinoid signaling Herpes simplex infection | details |
| TissueCFM000786 | protein import into mitochondrial outer membrane protein neddylation NEDD8_activating_enzyme_activity acid-amino acid ligase activity mitochondrial outer membrane translocase complex small protein activating enzyme activity Ubiquitin_Proteasome_system, E1: ThiF | details |
| TissueCFM000796 | Base excision repair | details |
| TissueCFM000797 | threonine-type endopeptidase activity proteolysis involved in cellular protein catabolic process proteasome core complex endopeptidase activity proteasome core complex, alpha-subunit complex ubiquitin-dependent protein catabolic process Proteasome Base excision repair | details |
| TissueCFM000812 | sucrose-phosphate phosphatase activity beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity sucrose biosynthetic process protein N-linked glycosylation protein folding formation of glycosidic bonds, GlycosylTransferases: GTnc sucrose biosynthesis II sucrose biosynthesis I (from photosynthesis) N-Glycan biosynthesis Glutathione metabolism Cationic antimicrobial peptide (CAMP) resistance | details |
| TissueCFM000873 | ubiquitin-specific_protease_activity peptidyl-prolyl cis-trans isomerase activity protein_peptidyl-prolyl_isomerization ubiquitin-dependent protein catabolic process signal transduction protein folding Ubiquitin_Proteasome_system, DUB: UCH | details |
| TissueCFM000877 | transcription_corepressor_activity Protein_kinases_phosphatases, PPC:1.16.1: Receptor Like Cytoplasmic Kinase II triacylglycerol degradation Retrograde endocannabinoid signaling Platinum drug resistance Endocrine resistance | details |
| TissueCFM000878 | Protein_kinases_phosphatases, PPC:1.16.1: Receptor Like Cytoplasmic Kinase II Transcription_related, Transcription factor: C2H2 | details |
| TissueCFM000904 | prefoldin complex lipoate biosynthetic process ribosome lipoate synthase activity aminoacyl-tRNA_editing_activity translation 4 iron, 4 sulfur cluster binding structural constituent of ribosome lipoate biosynthesis and incorporation II lipoate biosynthesis and incorporation I tRNA charging Lipoic acid metabolism Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001032 | TCA cycle II (plants and fungi) TCA cycle variation V (plant) Carbon fixation pathways in prokaryotes | details |
| TissueCFM001048 | beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity protein N-linked glycosylation mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) proton-transporting ATPase activity, rotational mechanism hydrogen ion transporting ATP synthase activity, rotational mechanism ATP synthesis coupled proton transport membrane formation of glycosidic bonds, GlycosylTransferases: GTnc N-Glycan biosynthesis | details |
| TissueCFM001157 | thiosulfate disproportionation III (rhodanese) Sulfur relay system | details |
| TissueCFM001174 | Cell cycle - yeast | details |
| TissueCFM001180 | protein N-linked glycosylation beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc N-Glycan biosynthesis | details |
| TissueCFM001181 | proteolysis involved in cellular protein catabolic process proteasome core complex threonine-type endopeptidase activity proteasome core complex, alpha-subunit complex endopeptidase activity ubiquitin-dependent protein catabolic process Ubiquitin_Proteasome_system, DUB: JAMM Proteasome | details |
| TissueCFM001183 | proteolysis involved in cellular protein catabolic process proteasome core complex threonine-type endopeptidase activity proteasome core complex, alpha-subunit complex endopeptidase activity ubiquitin-dependent protein catabolic process protein N-linked glycosylation beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity calmodulin binding formation of glycosidic bonds, GlycosylTransferases: GTnc Proteasome N-Glycan biosynthesis Alzheimer's disease | details |
| TissueCFM001184 | Arp2/3_protein_complex actin cytoskeleton Arp2/3_complex-mediated_actin_nucleation regulation of actin filament polymerization protein glycosylation galactosyltransferase activity Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII formation of glycosidic bonds, GlycosylTransferases: GTnc Glycosaminoglycan biosynthesis - heparan sulfate / heparin Platinum drug resistance | details |
| TissueCFM001211 | proteasomal ubiquitin-dependent protein catabolic process nucleotide-excision repair tRNA aminoacylation for protein translation damaged DNA binding tRNA charging Aminoacyl-tRNA biosynthesis | details |
| TissueCFM001286 | Cdc73/Paf1 complex histone modification transcription elongation from RNA polymerase II promoter galactosyltransferase activity cellular amino acid metabolic process protein glycosylation methyltransferase activity formation of glycosidic bonds, GlycosylTransferases: GTnc thiosulfate disproportionation III (rhodanese) homoserine biosynthesis Sulfur relay system Monobactam biosynthesis Glycosaminoglycan biosynthesis - heparan sulfate / heparin | details |
| TissueCFM001359 | transcription elongation from RNA polymerase II promoter Golgi vesicle transport histone modification vesicle docking Cdc73/Paf1 complex protein glycosylation exocytosis galactosyltransferase activity endoplasmic reticulum Protein_kinases_phosphatases, PPC:1.2.2: Receptor Like Cytoplasmic Kinase VII formation of glycosidic bonds, GlycosylTransferases: GTnc Glycosaminoglycan biosynthesis - heparan sulfate / heparin | details |
| TissueCFM001383 | protein_prenylation protein N-linked glycosylation via asparagine protein prenyltransferase activity endoplasmic reticulum membrane protein ubiquitination cell redox homeostasis Protein processing in endoplasmic reticulum Vibrio cholerae infection | details |
| TissueCFM001426 | ATP-dependent peptidase activity galactosyltransferase activity protein glycosylation helicase activity formation of glycosidic bonds, GlycosylTransferases: GTnc Glycosaminoglycan biosynthesis - heparan sulfate / heparin Herpes simplex infection | details |
| TissueCFM001431 | CAAX-box_protein_processing phosphatidylinositol phosphorylation metalloendopeptidase activity peptidase activity D-myo-inositol (1,4,5)-trisphosphate degradation Phosphatidylinositol signaling system Terpenoid backbone biosynthesis | details |
| TissueCFM001505 | actin_filament_depolymerization protein N-linked glycosylation beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity actin binding isomerase activity actin cytoskeleton formation of glycosidic bonds, GlycosylTransferases: GTnc N-Glycan biosynthesis Cationic antimicrobial peptide (CAMP) resistance | details |
Expression profiles
 Show details about module gene expression profiling |